Members

Joined: October 2021

My research focuses on understanding the molecular architecture of plant circadian clocks using mathematical and computational approaches.
I develop and analyze large-scale ordinary differential equation (ODE) models of the plant circadian regulatory network to uncover how feedback loops, transcriptional repression, protein degradation, and environmental inputs collectively generate robust ~24-hour rhythms. My work integrates computational modeling with transcriptomic data and network analysis to identify key regulatory mechanisms governing timing, robustness, and seasonal adaptation.
Through comparative studies across species, I aim to reveal fundamental design principles of plant circadian systems and understand how these biological clocks adapt to diverse environmental conditions.

Research Interest: Understanding seasonal adaptation through circadian regulatory network in Arabidopsis using mathematical modelling.

Joined: January 2022

I’m a PhD scholar at IIT Gandhinagar exploring how circadian rhythms, gene networks, and muscle biology intersect. My work ranges from studying the structural mechanisms of small molecules activity, network analysis of time-course gene expression data samples, to studying the structural interplay between MYOD1 and BMAL1.

Living with a myopathic rare condition has shaped my scientific path and strengthened my commitment to rare disease advocacy. Through NGOs like BharathMD (India) and IndoUSRare (USA), I volunteer to amplify rare disease research in India, help organize genetic testing camps, build awareness, and connect science with real lives. I also enjoy sharing science through writing, including contributions to SAMAY, the chronobiology newsletter.

I love to crack bad jokes, dad jokes, and random jokes. Not joking!

Research Interest: Computational analysis of peripheral circadian regulatory networks

Joined: January 2023

I am a graduate student in the Computational Biology Lab since 2022. I pursued my Integrative Masters degree in Bioinformatics.

Research Interest: My academic journey has been driven by a keen interest in understanding macromolecular structures and dynamics using computational techniques. Currently, my work focuses on delineating the functional role of the core transcription factor, which regulates the circadian rhythm.

Joined: January 2024

I have a Master’s degree in Biotechnology from MSU Baroda. I am primarily interested in proteins structure-function relationship. My larger goal is to use structural biology approach for therapeutic interventions for autoimmunity.

Research Interest: My work at CLOCK lab revolves around REV-ERBs, which are nuclear receptors involved in circadian rhythms. Using molecular dynamics simulations as well as wet-lab methods, we want to understand, compare and contrast the structures of REV-ERB isoforms when they are in their ligand-bound and unbound states.

Joined: December 2024

Pooja Roham is a PhD scholar studying cancer biology in our lab. Her work combines computational and experimental approaches to explore the circadian link to cancer. She is particularly interested in finding better treatment and diagnosis methods.

Research Interest: Circadian Clock as target for Oral Cancer

Joined: July 2024

I am a PhD candidate investigating the molecular mechanisms of Tau protein aggregation in various Tauopathies. In my research, I use all-atom Molecular Dynamics (MD) simulations to look at how these proteins misfold and interact. Ultimately, my goal is to identify and characterize small molecule modulators that can effectively disrupt these aggregation pathways.
When I’m not at the workspace(or more accurately, the terminal), I am a massive tech and hardware nerd with a particular love for Linux. In my downtime, you can usually find me gaming, tinkering with my setup, or playing the guitar.

Research Interest: Tau Protein Aggregation | Molecular Dynamics | High Performance Computing