{"id":437,"date":"2025-11-21T20:18:40","date_gmt":"2025-11-21T20:18:40","guid":{"rendered":"https:\/\/research.iitgn.ac.in\/compbio\/?page_id=437"},"modified":"2026-03-11T18:09:25","modified_gmt":"2026-03-11T18:09:25","slug":"members","status":"publish","type":"page","link":"https:\/\/research.iitgn.ac.in\/compbio\/members\/","title":{"rendered":"Members"},"content":{"rendered":"\n
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Ashutosh Srivastava, Principal Invesitgator<\/h3>\n\n\n\n

Assistant Professor, IIT Gandhinagar<\/p>\n<\/div>\n\n\n\n

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PhD Scholars<\/h2>\n\n\n\n
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Shashank Kumar Singh<\/h3><\/div>\n\n\n\n
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Joined:<\/strong> October 2021<\/p>\n\n\n\n

My research focuses on understanding the molecular architecture of plant circadian clocks using mathematical and computational approaches.
I develop and analyze large-scale ordinary differential equation (ODE) models of the plant circadian regulatory network to uncover how feedback loops, transcriptional repression, protein degradation, and environmental inputs collectively generate robust ~24-hour rhythms. My work integrates computational modeling with transcriptomic data and network analysis to identify key regulatory mechanisms governing timing, robustness, and seasonal adaptation.
Through comparative studies across species, I aim to reveal fundamental design principles of plant circadian systems and understand how these biological clocks adapt to diverse environmental conditions.<\/p>\n\n\n\n

Research Interest:<\/strong> Understanding seasonal adaptation through circadian regulatory network in Arabidopsis using mathematical modelling.<\/p>\n<\/div>\n\n\n\n

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Shriyansh Srivastava<\/h3><\/div>\n\n\n\n
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Joined:<\/strong> January 2022<\/p>\n\n\n\n

I\u2019m a PhD scholar at IIT Gandhinagar exploring how circadian rhythms, gene networks, and muscle biology intersect. My work ranges from studying the structural mechanisms of small molecules activity, network analysis of time-course gene expression data samples, to studying the structural interplay between MYOD1 and BMAL1.<\/p>\n\n\n\n

Living with a myopathic rare condition has shaped my scientific path and strengthened my commitment to rare disease advocacy. Through NGOs like BharathMD (India) and IndoUSRare (USA), I volunteer to amplify rare disease research in India, help organize genetic testing camps, build awareness, and connect science with real lives. I also enjoy sharing science through writing, including contributions to SAMAY, the chronobiology newsletter.<\/p>\n\n\n\n

I love to crack bad jokes, dad jokes, and random jokes. Not joking!<\/p>\n\n\n\n

Research Interest:<\/strong> Computational analysis of peripheral circadian regulatory networks<\/p>\n<\/div>\n\n\n\n

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Karthik S.<\/h3><\/div>\n\n\n\n
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Joined:<\/strong> January 2023<\/p>\n\n\n\n

I am a graduate student in the Computational Biology Lab since 2022. I pursued my Integrative Masters degree in Bioinformatics.<\/p>\n\n\n\n

Research Interest:<\/strong> My academic journey has been driven by a keen interest in understanding macromolecular structures and dynamics using computational techniques. Currently, my work focuses on delineating the functional role of the core transcription factor, which regulates the circadian rhythm.<\/p>\n<\/div>\n\n\n\n

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Yashasvi Rao<\/h3><\/div>\n\n\n\n
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Joined: <\/strong>January 2024<\/p>\n\n\n\n

I have a Master’s degree in Biotechnology from MSU Baroda. I am primarily interested in proteins structure-function relationship. My larger goal is to use structural biology approach for therapeutic interventions for autoimmunity.<\/p>\n\n\n\n

Research Interest:<\/strong> My work at CLOCK lab revolves around REV-ERBs, which are nuclear receptors involved in circadian rhythms. Using molecular dynamics simulations as well as wet-lab methods, we want to understand, compare and contrast the structures of REV-ERB isoforms when they are in their ligand-bound and unbound states.<\/p>\n<\/div>\n\n\n\n

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Pooja Roham<\/h3><\/div>\n\n\n\n
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Joined: <\/strong>December 2024<\/p>\n\n\n\n

Pooja Roham is a PhD scholar studying cancer biology in our lab. Her work combines computational and experimental approaches to explore the circadian link to cancer. She is particularly interested in finding better treatment and diagnosis methods.<\/p>\n\n\n\n

Research Interest:<\/strong> Circadian Clock as target for Oral Cancer<\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

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Prithvinath Gollakota<\/h3><\/div>\n\n\n\n
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Joined: <\/strong>July 2024<\/p>\n\n\n\n

I am a PhD candidate investigating the molecular mechanisms of Tau protein aggregation in various Tauopathies. In my research, I use all-atom Molecular Dynamics (MD) simulations to look at how these proteins misfold and interact. Ultimately, my goal is to identify and characterize small molecule modulators that can effectively disrupt these aggregation pathways.
When I\u2019m not at the workspace(or more accurately, the terminal), I am a massive tech and hardware nerd with a particular love for Linux. In my downtime, you can usually find me gaming, tinkering with my setup, or playing the guitar.<\/p>\n\n\n\n

Research Interest:<\/strong> Tau Protein Aggregation | Molecular Dynamics | High Performance Computing <\/p>\n<\/div>\n\n\n\n

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MTech Students<\/h2>\n\n\n\n
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Aditi Moharana<\/h3><\/div>\n\n\n\n
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Joined:<\/strong> July 2024<\/p>\n\n\n\n

M.Tech 2nd year | Membrane proteins | Molecular Dynamics Simulations<\/p>\n\n\n\n

Research Interest:<\/strong> Understanding the molecular mechanisms in membrane associated proteins<\/p>\n<\/div>\n\n\n\n

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Vaishnavi Tiwari<\/h3><\/div>\n\n\n\n
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Joined: <\/strong>July 2024<\/p>\n\n\n\n

I’m a Master’s student at IIT Gandhinagar trying to understand dysregulated pathways in a rare genetic condition called Facioscapulohumeral muscular dystrophy.
Apart from this, I’m also keen on exploring the role of circadian rhythms in disease etiology, especially rare diseases.<\/p>\n\n\n\n

Research Interest:<\/strong> Transcriptomics, Rare diseases, Single-cell RNA sequencing analysis<\/p>\n<\/div>\n\n\n\n

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Kaushal S<\/h3><\/div>\n\n\n\n
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Joined: <\/strong>July 2025<\/p>\n\n\n\n

Biotechnology student with experience in computational biology and drug design. Broadly interested in understanding biomolecular mechanisms and developing solutions in healthcare and biotechnology.<\/p>\n\n\n\n

Research Interest:<\/strong> Biomolecular interactions based on glycoproteins and Rev-Erbs<\/p>\n<\/div>\n\n\n\n

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Shreya<\/h3><\/div>\n\n\n\n
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Joined: <\/strong>July 2025<\/p>\n\n\n\n

I am an M.Tech student working in computational structural biology, applying molecular modeling and simulation strategies to decipher how ligand\u2013receptor interactions govern biological signaling. Essentially, I put atoms in a box and see if they talk back. When not in the lab, I can usually be found doodling with coffee in hand.<\/p>\n\n\n\n

Research Interest:<\/strong> I am investigating the activation mechanism of the allatostatin receptor, a G protein\u2013coupled receptor (GPCR) that regulates insect metabolism and represents an emerging target for selective pest control. I employ molecular dynamics simulations and docking approaches to examine its conformational dynamics and ligand\u2013receptor interactions at an atomic resolution.<\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

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Bibhu Prasad Sahoo<\/h3><\/div>\n\n\n\n
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Joined: <\/strong>July 2025<\/p>\n\n\n\n

I am a Master\u2019s student at IIT Gandhinagar investigating how plant gene regulatory networks respond to varying natural light and temperature conditions. My research focuses on developing and analyzing mathematical models\u2014primarily using ordinary differential equations (ODEs) and nonlinear dynamics\u2014to capture and understand these regulatory responses.<\/p>\n\n\n\n

Research Interest:<\/strong> Systems Biology, Mathematical Modeling, Nonlinear Dynamical Systems, Gene Regulatory Networks, Computational Biology<\/p>\n<\/div>\n\n\n\n

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Postdoctoral Fellows<\/h2>\n\n\n\n
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Dr. C. Nithya<\/h3><\/div>\n\n\n\n
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Joined:<\/strong> June 2025<\/p>\n\n\n\n

A bioinformatics researcher with ~ 8 years of experience in network biology especially protein\u2013protein interaction networks.<\/p>\n\n\n\n

Research Interest:<\/strong> Network Biology (Protein-Protein interaction networks), Multi-omics Data Integration\/ Currently, I am modeling 12 mammalian bHLH\u2013PAS transcription factor complexes as Protein Contact Networks to systematically capture their residue-level interactions. This network-based framework enables comparative analysis of key contact patterns, structural features, and critical residues that govern the stability and function of these complexes<\/p>\n<\/div>\n\n\n\n

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Alumni<\/h2>\n\n\n\n
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Rakesh Thakur<\/p>\n\n\n\n

2021 – 2022<\/p>\n<\/div>\n<\/div><\/div>\n\n\n\n

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Siddhi Patil<\/p>\n\n\n\n

2022 – 2023<\/p>\n<\/div>\n<\/div><\/div>\n\n\n\n

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Vidya Sundaram<\/p>\n\n\n\n

2021 – 2023<\/p>\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

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Pritam Biswas<\/p>\n\n\n\n

2023<\/p>\n<\/div>\n<\/div><\/div>\n\n\n\n

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Shrusti Doshi<\/p>\n\n\n\n

July 2023 \u2013 August 2023<\/p>\n<\/div>\n<\/div><\/div>\n\n\n\n

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Sayantoni Chadhuri<\/p>\n\n\n\n

January 2021 \u2013 December 2023<\/p>\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

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Vidushi Aggarwal<\/p>\n\n\n\n

July 2022 – June 2024<\/p>\n<\/div>\n<\/div><\/div>\n\n\n\n

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Rahul Nair<\/p>\n\n\n\n

July 2023 \u2013 August 2025<\/p>\n<\/div>\n<\/div><\/div>\n\n\n\n

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Vishnu A M<\/p>\n\n\n\n

July 2023 \u2013 August 2025<\/p>\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

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Ramanujan Simha<\/p>\n\n\n\n

September 2024 – April 2025<\/p>\n<\/div>\n<\/div><\/div>\n\n\n\n\n<\/div>\n<\/div><\/div>\n\n\n\n\n<\/div><\/div>\n\n\n\n

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Ashutosh Srivastava, Principal Invesitgator Assistant Professor, IIT Gandhinagar Google Scholar Follow @AshuCompBio Ashutosh Srivastava, Principal Invesitgator Assistant Professor, IIT Gandhinagar Google Scholar Follow @AshuCompBio Connect on LinkedIn PhD Scholars Shashank Kumar Singh Joined: October 2021 My research focuses on understanding the molecular architecture of plant circadian clocks using mathematical and computational approaches.I develop and analyze […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","footnotes":""},"class_list":["post-437","page","type-page","status-publish","hentry"],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"Prithvinath Gollakota","author_link":"https:\/\/research.iitgn.ac.in\/compbio\/author\/prithvinath\/"},"uagb_comment_info":0,"uagb_excerpt":"Ashutosh Srivastava, Principal Invesitgator Assistant Professor, IIT Gandhinagar Google Scholar Follow @AshuCompBio Ashutosh Srivastava, Principal Invesitgator Assistant Professor, IIT Gandhinagar Google Scholar Follow @AshuCompBio Connect on LinkedIn PhD Scholars Shashank Kumar Singh Joined: October 2021 My research focuses on understanding the molecular architecture of plant circadian clocks using mathematical and computational approaches.I develop and analyze…","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/research.iitgn.ac.in\/compbio\/wp-json\/wp\/v2\/pages\/437","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/research.iitgn.ac.in\/compbio\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/research.iitgn.ac.in\/compbio\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/research.iitgn.ac.in\/compbio\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/research.iitgn.ac.in\/compbio\/wp-json\/wp\/v2\/comments?post=437"}],"version-history":[{"count":80,"href":"https:\/\/research.iitgn.ac.in\/compbio\/wp-json\/wp\/v2\/pages\/437\/revisions"}],"predecessor-version":[{"id":679,"href":"https:\/\/research.iitgn.ac.in\/compbio\/wp-json\/wp\/v2\/pages\/437\/revisions\/679"}],"wp:attachment":[{"href":"https:\/\/research.iitgn.ac.in\/compbio\/wp-json\/wp\/v2\/media?parent=437"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}